Aprepitant-d4(Aprepitant-d4) is a chemical substance in which several hydrogen atoms in its chemical structure are replaced by heavy hydrogen (D). It is an isotope-labeled compound of Aprepitant.
The Aprepitant-d4 is mainly used to study drug metabolism, pharmacokinetics and drug interactions. By using Aprepitant-d4, the metabolic pathway and rate of a drug in the body can be tracked to better understand its mechanism of action.
The preparation method of the Aprepitant-d4 includes using a chemical reaction to replace the hydrogen atoms in Arry with heavy hydrogen atoms. The deuterating reagent is usually reacted with Arry under suitable reaction conditions to generate Aprepitant-d4.
For safety information, Aprepitant-d4 toxicity, side effects, and safety are similar to ARI itself. However, because it is an isotopically labeled compound, its availability as a drug is low, and it is mainly used for scientific research. Follow laboratory safety regulations, avoid direct contact and ingestion, and properly store and dispose of waste. If you need to use Aprepitant-d4, it is recommended to consult relevant experts or institutions to ensure safe and compliant use.